The Effects of Methylphenidate on Transcranial Magnetic Stimulation Parameters in Children with Attention Deficit Hyperactivity Disorder
نویسندگان
چکیده
Attention deficit hyperactivity disorder (ADHD) is a common psychiatric disorder of childhood with the core symptoms of developmentally inappropriate levels of attention, hyperactivity, and impulsivity. One of the essential theories proposes that ADHD is most often the result of dysfunction in fronto-striatal motor intentional circuits that are critical for an organism’s “preparedness of acts” associated with impairments in information processing (1,2). ADHD is associated with deficits in response selection, motor response preparation, motor response inhibition, motor persistence, motor adjustment, and inhibition of prepotent responses (2-6). Stimulants are most widely prescribed drugs in children with ADHD and highly effective in alleviating ADHD symptoms (7). Methylphenidate (MPH) is a short acting compound, with an onset of action within 30 to 60 The Effects of Methylphenidate on Transcranial Magnetic Stimulation Parameters in Children with Attention Deficit Hyperactivity Disorder
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